CD28 protein (Felis catus) - STRING interaction network

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CD28

T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation. (255 aa)

Predicted Functional Partners:

CD86

0.996

CD80

0.995

PIK3R1

0.987

GRB2

0.982

PIK3R2

0.964

PIK3R3

0.964

PIK3CA

0.944

PRKCQ

0.940

ICOSLG

0.934

PIK3CD

0.933

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD28	CD80	ENSFCAP00000013242	ENSFCAP00000008890	T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.	B-lymphocyte activation antigen B7-1 (CD80).	0.995
CD28	CD86	ENSFCAP00000013242	ENSFCAP00000059492	T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.	B-lymphocyte activation antigen B7-2 (CD86).	0.996
CD28	GRB2	ENSFCAP00000013242	ENSFCAP00000023767	T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.	Growth factor receptor bound protein 2.	0.982
CD28	ICOSLG	ENSFCAP00000013242	ENSFCAP00000056949	T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.	Ig-like domain-containing protein.	0.934
CD28	PIK3CA	ENSFCAP00000013242	ENSFCAP00000037527	T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.944
CD28	PIK3CD	ENSFCAP00000013242	ENSFCAP00000023559	T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.933
CD28	PIK3R1	ENSFCAP00000013242	ENSFCAP00000010244	T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.	Phosphoinositide-3-kinase regulatory subunit 1.	0.987
CD28	PIK3R2	ENSFCAP00000013242	ENSFCAP00000043558	T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.	Phosphoinositide-3-kinase regulatory subunit 2.	0.964
CD28	PIK3R3	ENSFCAP00000013242	ENSFCAP00000046758	T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.	Uncharacterized protein.	0.964
CD28	PRKCQ	ENSFCAP00000013242	ENSFCAP00000041019	T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.940
CD80	CD28	ENSFCAP00000008890	ENSFCAP00000013242	B-lymphocyte activation antigen B7-1 (CD80).	T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.	0.995
CD80	CD86	ENSFCAP00000008890	ENSFCAP00000059492	B-lymphocyte activation antigen B7-1 (CD80).	B-lymphocyte activation antigen B7-2 (CD86).	0.998
CD80	GRB2	ENSFCAP00000008890	ENSFCAP00000023767	B-lymphocyte activation antigen B7-1 (CD80).	Growth factor receptor bound protein 2.	0.576
CD80	ICOSLG	ENSFCAP00000008890	ENSFCAP00000056949	B-lymphocyte activation antigen B7-1 (CD80).	Ig-like domain-containing protein.	0.406
CD80	PIK3CA	ENSFCAP00000008890	ENSFCAP00000037527	B-lymphocyte activation antigen B7-1 (CD80).	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.544
CD80	PIK3R1	ENSFCAP00000008890	ENSFCAP00000010244	B-lymphocyte activation antigen B7-1 (CD80).	Phosphoinositide-3-kinase regulatory subunit 1.	0.518
CD80	PIK3R2	ENSFCAP00000008890	ENSFCAP00000043558	B-lymphocyte activation antigen B7-1 (CD80).	Phosphoinositide-3-kinase regulatory subunit 2.	0.518
CD80	PIK3R3	ENSFCAP00000008890	ENSFCAP00000046758	B-lymphocyte activation antigen B7-1 (CD80).	Uncharacterized protein.	0.518
CD86	CD28	ENSFCAP00000059492	ENSFCAP00000013242	B-lymphocyte activation antigen B7-2 (CD86).	T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.	0.996
CD86	CD80	ENSFCAP00000059492	ENSFCAP00000008890	B-lymphocyte activation antigen B7-2 (CD86).	B-lymphocyte activation antigen B7-1 (CD80).	0.998

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