STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2HGDHD-2-hydroxyglutarate dehydrogenase. (541 aa)    
Predicted Functional Partners:
MEAF6
MYST/Esa1 associated factor 6.
   
 0.842
TRRAP
Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.
   
 0.824
DMAP1
DNA methyltransferase 1 associated protein 1.
   
 0.816
YEATS4
YEATS domain containing 4.
   
 0.763
MAT2B
Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.
 
    
 0.759
L2HGDH
L-2-hydroxyglutarate dehydrogenase.
      
 0.743
EPC2
Enhancer of polycomb homolog.
   
 0.715
EPC1
Enhancer of polycomb homolog.
   
 0.715
ACTL6B
Actin like 6B; Belongs to the actin family.
   
 0.680
ACTL6A
Actin like 6A; Belongs to the actin family.
   
 0.680
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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