Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRRC14Leucine rich repeat containing 14. (503 aa)    
Predicted Functional Partners:
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
  0.939
CUL2
Cullin 2; Belongs to the cullin family.
    
 
 0.823
COPS5
COP9 signalosome subunit 5.
    
   0.818
COPS3
COP9 signalosome subunit 3.
    
   0.803
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
  0.800
WDR74
WD repeat domain 74.
      
 0.653
ALG12
Mannosyltransferase.
   
  
 0.647
COPS6
MPN domain-containing protein.
    
   0.615
ENSFCAP00000026104
MPN domain-containing protein.
    
   0.615
PIK3IP1
Phosphoinositide-3-kinase interacting protein 1.
      
 0.609
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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