| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CYP2J2 | EPHX2 | ENSFCAP00000056975 | ENSFCAP00000013376 | Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. | Epoxide hydrolase 2. | 0.957 |
| CYP2J2 | LOC105259649 | ENSFCAP00000056975 | ENSFCAP00000036747 | Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.921 |
| CYP2J2 | LOC105260134 | ENSFCAP00000056975 | ENSFCAP00000041199 | Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.920 |
| EPHX2 | CYP2J2 | ENSFCAP00000013376 | ENSFCAP00000056975 | Epoxide hydrolase 2. | Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. | 0.957 |
| EPHX2 | GMPR | ENSFCAP00000013376 | ENSFCAP00000009749 | Epoxide hydrolase 2. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.846 |
| EPHX2 | IMPDH1 | ENSFCAP00000013376 | ENSFCAP00000000883 | Epoxide hydrolase 2. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.846 |
| EPHX2 | IMPDH2 | ENSFCAP00000013376 | ENSFCAP00000009132 | Epoxide hydrolase 2. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.847 |
| EPHX2 | LOC105259649 | ENSFCAP00000013376 | ENSFCAP00000036747 | Epoxide hydrolase 2. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.918 |
| EPHX2 | LOC105260134 | ENSFCAP00000013376 | ENSFCAP00000041199 | Epoxide hydrolase 2. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.918 |
| EPHX2 | MTAP | ENSFCAP00000013376 | ENSFCAP00000034359 | Epoxide hydrolase 2. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.875 |
| EPHX2 | NUDT12 | ENSFCAP00000013376 | ENSFCAP00000012695 | Epoxide hydrolase 2. | Nudix hydrolase 12. | 0.863 |
| EPHX2 | PNP | ENSFCAP00000013376 | ENSFCAP00000006438 | Epoxide hydrolase 2. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.877 |
| EPHX2 | QRICH1 | ENSFCAP00000013376 | ENSFCAP00000009133 | Epoxide hydrolase 2. | Glutamine rich 1. | 0.846 |
| GMPR | EPHX2 | ENSFCAP00000009749 | ENSFCAP00000013376 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Epoxide hydrolase 2. | 0.846 |
| GMPR | IMPDH1 | ENSFCAP00000009749 | ENSFCAP00000000883 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.948 |
| GMPR | IMPDH2 | ENSFCAP00000009749 | ENSFCAP00000009132 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.916 |
| GMPR | MTAP | ENSFCAP00000009749 | ENSFCAP00000034359 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.684 |
| GMPR | PNP | ENSFCAP00000009749 | ENSFCAP00000006438 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.612 |
| IMPDH1 | EPHX2 | ENSFCAP00000000883 | ENSFCAP00000013376 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | Epoxide hydrolase 2. | 0.846 |
| IMPDH1 | GMPR | ENSFCAP00000000883 | ENSFCAP00000009749 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.948 |