CLU protein (Felis catus) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

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Score

CLU

Clusterin; Belongs to the clusterin family. (469 aa)

Predicted Functional Partners:

APP

0.817

TREM2

0.781

APOA1

0.719

XRCC6

0.685

LRP2

0.684

VLDLR

0.682

BIN1

0.680

LTF

0.661

PON1

0.653

CD59

0.651

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOA1	APP	ENSFCAP00000016102	ENSFCAP00000001445	Apolipoprotein A1.	Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...]	0.569
APOA1	CLU	ENSFCAP00000016102	ENSFCAP00000013377	Apolipoprotein A1.	Clusterin; Belongs to the clusterin family.	0.719
APOA1	LTF	ENSFCAP00000016102	ENSFCAP00000013454	Apolipoprotein A1.	Lactotransferrin; Belongs to the transferrin family.	0.614
APOA1	PON1	ENSFCAP00000016102	ENSFCAP00000035990	Apolipoprotein A1.	Paraoxonase 1.	0.638
APOA1	VLDLR	ENSFCAP00000016102	ENSFCAP00000052084	Apolipoprotein A1.	Very low density lipoprotein receptor.	0.672
APP	APOA1	ENSFCAP00000001445	ENSFCAP00000016102	Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...]	Apolipoprotein A1.	0.569
APP	CLU	ENSFCAP00000001445	ENSFCAP00000013377	Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...]	Clusterin; Belongs to the clusterin family.	0.817
APP	LRP2	ENSFCAP00000001445	ENSFCAP00000005687	Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...]	LDL receptor related protein 2.	0.423
APP	TREM2	ENSFCAP00000001445	ENSFCAP00000002549	Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...]	Triggering receptor expressed on myeloid cells 2.	0.627
APP	VLDLR	ENSFCAP00000001445	ENSFCAP00000052084	Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...]	Very low density lipoprotein receptor.	0.442
BIN1	CLU	ENSFCAP00000037575	ENSFCAP00000013377	Bridging integrator 1.	Clusterin; Belongs to the clusterin family.	0.680
CD59	CLU	ENSFCAP00000056596	ENSFCAP00000013377	UPAR/Ly6 domain-containing protein.	Clusterin; Belongs to the clusterin family.	0.651
CLU	APOA1	ENSFCAP00000013377	ENSFCAP00000016102	Clusterin; Belongs to the clusterin family.	Apolipoprotein A1.	0.719
CLU	APP	ENSFCAP00000013377	ENSFCAP00000001445	Clusterin; Belongs to the clusterin family.	Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...]	0.817
CLU	BIN1	ENSFCAP00000013377	ENSFCAP00000037575	Clusterin; Belongs to the clusterin family.	Bridging integrator 1.	0.680
CLU	CD59	ENSFCAP00000013377	ENSFCAP00000056596	Clusterin; Belongs to the clusterin family.	UPAR/Ly6 domain-containing protein.	0.651
CLU	LRP2	ENSFCAP00000013377	ENSFCAP00000005687	Clusterin; Belongs to the clusterin family.	LDL receptor related protein 2.	0.684
CLU	LTF	ENSFCAP00000013377	ENSFCAP00000013454	Clusterin; Belongs to the clusterin family.	Lactotransferrin; Belongs to the transferrin family.	0.661
CLU	PON1	ENSFCAP00000013377	ENSFCAP00000035990	Clusterin; Belongs to the clusterin family.	Paraoxonase 1.	0.653
CLU	TREM2	ENSFCAP00000013377	ENSFCAP00000002549	Clusterin; Belongs to the clusterin family.	Triggering receptor expressed on myeloid cells 2.	0.781