STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESCO2Establishment of sister chromatid cohesion N-acetyltransferase 2. (602 aa)    
Predicted Functional Partners:
SMC3
Structural maintenance of chromosomes protein.
   
 0.974
RAD21
RAD21 cohesin complex component.
   
 0.922
PDS5B
PDS5 cohesin associated factor B.
   
 0.890
SMC2
Structural maintenance of chromosomes 2.
   
 0.877
PDS5A
PDS5 cohesin associated factor A.
   
 0.853
SMC1A
Structural maintenance of chromosomes protein.
   
 0.847
SMC1B
Structural maintenance of chromosomes protein.
   
 0.837
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
  
 0.831
DLGAP5
DLG associated protein 5.
   
    0.825
DDX11
DEAD/H-box helicase 11.
   
 
 0.822
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.