PBK protein (Felis catus) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

PBK

PDZ binding kinase. (337 aa)

Predicted Functional Partners:

BIRC5

0.967

BUB1B

0.934

KIF11

0.932

NDC80

0.928

RRM2

0.919

KIF20A

0.917

DLGAP5

0.916

MELK

0.916

NUSAP1

0.911

TOP2A

0.907

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BIRC5	BUB1B	ENSFCAP00000038330	ENSFCAP00000057394	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	BUB1 mitotic checkpoint serine/threonine kinase B.	0.959
BIRC5	DLGAP5	ENSFCAP00000038330	ENSFCAP00000015423	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	DLG associated protein 5.	0.911
BIRC5	KIF11	ENSFCAP00000038330	ENSFCAP00000005778	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.919
BIRC5	KIF20A	ENSFCAP00000038330	ENSFCAP00000001584	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.957
BIRC5	MELK	ENSFCAP00000038330	ENSFCAP00000051077	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	Non-specific serine/threonine protein kinase.	0.865
BIRC5	NDC80	ENSFCAP00000038330	ENSFCAP00000016862	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	NDC80 kinetochore complex component.	0.856
BIRC5	NUSAP1	ENSFCAP00000038330	ENSFCAP00000011700	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	Nucleolar and spindle associated protein 1.	0.902
BIRC5	PBK	ENSFCAP00000038330	ENSFCAP00000013381	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	PDZ binding kinase.	0.967
BIRC5	RRM2	ENSFCAP00000038330	ENSFCAP00000003637	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	Ribonucleotide reductase regulatory subunit M2.	0.902
BIRC5	TOP2A	ENSFCAP00000038330	ENSFCAP00000008944	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.971
BUB1B	BIRC5	ENSFCAP00000057394	ENSFCAP00000038330	BUB1 mitotic checkpoint serine/threonine kinase B.	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	0.959
BUB1B	DLGAP5	ENSFCAP00000057394	ENSFCAP00000015423	BUB1 mitotic checkpoint serine/threonine kinase B.	DLG associated protein 5.	0.965
BUB1B	KIF11	ENSFCAP00000057394	ENSFCAP00000005778	BUB1 mitotic checkpoint serine/threonine kinase B.	Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.984
BUB1B	KIF20A	ENSFCAP00000057394	ENSFCAP00000001584	BUB1 mitotic checkpoint serine/threonine kinase B.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.967
BUB1B	MELK	ENSFCAP00000057394	ENSFCAP00000051077	BUB1 mitotic checkpoint serine/threonine kinase B.	Non-specific serine/threonine protein kinase.	0.887
BUB1B	NDC80	ENSFCAP00000057394	ENSFCAP00000016862	BUB1 mitotic checkpoint serine/threonine kinase B.	NDC80 kinetochore complex component.	0.984
BUB1B	NUSAP1	ENSFCAP00000057394	ENSFCAP00000011700	BUB1 mitotic checkpoint serine/threonine kinase B.	Nucleolar and spindle associated protein 1.	0.951
BUB1B	PBK	ENSFCAP00000057394	ENSFCAP00000013381	BUB1 mitotic checkpoint serine/threonine kinase B.	PDZ binding kinase.	0.934
BUB1B	RRM2	ENSFCAP00000057394	ENSFCAP00000003637	BUB1 mitotic checkpoint serine/threonine kinase B.	Ribonucleotide reductase regulatory subunit M2.	0.957
BUB1B	TOP2A	ENSFCAP00000057394	ENSFCAP00000008944	BUB1 mitotic checkpoint serine/threonine kinase B.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.969