STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIAA1841KIAA1841. (718 aa)    
Predicted Functional Partners:
DNASE1L3
Deoxyribonuclease; Belongs to the DNase I family.
      
 0.592
EPHX2
Epoxide hydrolase 2.
      
 0.590
NICN1
Uncharacterized protein.
    
   0.544
CCDC85A
Coiled-coil domain containing 85A.
      
 0.524
TTLL1
Tubulin tyrosine ligase like 1.
    
   0.519
LRRC49
Leucine rich repeat containing 49.
    
   0.518
LETM2
Leucine zipper and EF-hand containing transmembrane protein 2.
      
 0.493
PAQR5
Progestin and adipoQ receptor family member 5.
      
 0.455
CDCA8
Cell division cycle associated 8.
      
 0.455
MED31
Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.452
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.