Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TMCO5ATransmembrane and coiled-coil domains 5A. (303 aa)    
Predicted Functional Partners:
RTF2
Replication termination factor 2.
   
  
 0.787
ATP6V1H
V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.
      
 0.703
YPEL5
Protein yippee-like; Belongs to the yippee family.
      
 0.703
SYBU
Syntabulin.
      
 0.702
RBM43
RNA binding motif protein 43.
      
 0.700
SLITRK3
SLIT and NTRK like family member 3.
      
 0.700
CD4H9orf43
Chromosome 9 open reading frame 43.
      
 0.674
CB4H12orf40
Chromosome B4 C12orf40 homolog.
      
 0.671
AK8
Adenylate kinase 8; Belongs to the adenylate kinase family.
   
  
 0.626
UBE3C
Ubiquitin protein ligase E3C.
      
 0.612
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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