Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RDH16Retinol dehydrogenase 16; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (344 aa)    
Predicted Functional Partners:
LRAT
Lecithin retinol acyltransferase.
   
 
 0.895
BCO1
Beta-carotene oxygenase 1.
     
 0.868
PNPLA4
Patatin like phospholipase domain containing 4.
     
 0.867
ALDH1A3
Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.
     
 0.866
ALDH1A2
Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.
     
 0.865
ALDH1A1
Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family.
     
 0.864
RETSAT
Retinol saturase.
   
 
 0.862
CYP27C1
Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family.
    
 0.860
AWAT2
Acyl-CoA wax alcohol acyltransferase 2.
   
 
  0.860
AOX1
Uncharacterized protein.
     
 0.841
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (24%) [HD]