Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM189A2Family with sequence similarity 189 member A2. (610 aa)    
Predicted Functional Partners:
WWP2
E3 ubiquitin-protein ligase.
    
  0.832
WWP1
E3 ubiquitin-protein ligase.
    
  0.799
CDK18
Cyclin dependent kinase 18.
   
 
 0.774
ITCH
E3 ubiquitin-protein ligase.
    
  0.723
ANKS1A
Ankyrin repeat and sterile alpha motif domain containing 1A.
    
 0.717
CNOT2
CCR4-NOT transcription complex subunit 2.
   
  
 0.681
FAM189B
Family with sequence similarity 189 member B.
    
 
 0.651
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
    
  0.633
SOWAHA
Sosondowah ankyrin repeat domain family member A.
    
 0.626
COL4A2
Collagen type IV alpha 2 chain.
    
 0.616
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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