Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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[Homology]
Score
M3WL30_FELCABeta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (73 aa)    
Predicted Functional Partners:
DEFB124
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.718
DEFB1
Defensin beta 1.
     
 0.710
LOC101101212
Uncharacterized protein.
     
 0.682
DEFB112
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.626
DEFB119
Defensin beta 119.
     
 0.611
ENSFCAP00000041110
Uncharacterized protein.
     
 0.602
DEFB110
Defensin beta 110.
     
 0.576
LOC109498699
Uncharacterized protein.
     
 0.524
ENSFCAP00000038598
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.521
ENSFCAP00000057561
Uncharacterized protein.
     
 0.519
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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