Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DEFB124Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (70 aa)    
Predicted Functional Partners:
DEFB125
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.913
DEFB113
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.879
DEFB123
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.873
DEFB128
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.847
DEFB116
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.823
ANXA2
Annexin.
    
   0.808
ENSFCAP00000038598
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.776
ENSFCAP00000057561
Uncharacterized protein.
     
 0.770
DEFB119
Defensin beta 119.
     
 0.741
M3WL30_FELCA
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.718
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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