Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RCOR2REST corepressor 2. (523 aa)    
Predicted Functional Partners:
KDM1A
Lysine demethylase 1A.
   
 0.930
HMG20B
High mobility group 20B.
   
 0.898
PHF21A
PHD finger protein 21A.
   
 0.861
HMG20A
High mobility group 20A.
   
 0.859
REST
RE1 silencing transcription factor.
    
 0.850
RCOR1
REST corepressor 1.
   
   0.725
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.710
HDAC2
Histone deacetylase 2.
    
 0.710
ZMYM2
Zinc finger MYM-type containing 2.
   
 
 0.703
SNAI1
Snail family transcriptional repressor 1.
    
 0.698
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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