Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HM13Histocompatibility minor 13. (421 aa)    
Predicted Functional Partners:
RNF139
Ring finger protein 139.
   
 
 0.874
DERL1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
 
 0.801
HMOX1
Heme oxygenase 1.
     
 0.799
SSR3
Signal sequence receptor subunit 3.
   
 
 0.704
CCNB1IP1
Cyclin B1 interacting protein 1.
      
 0.692
SSR2
Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
   
 
 0.668
HSP90B1
Heat shock protein 90 beta family member 1.
   
  
 0.613
SEC63
SEC63 homolog, protein translocation regulator.
   
 
 0.610
STT3A
STT3 oligosaccharyltransferase complex catalytic subunit A.
   
 
 0.600
HMOX2
Heme oxygenase 2.
     
 0.595
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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