HM13 protein (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

HM13

Histocompatibility minor 13. (421 aa)

Predicted Functional Partners:

HMOX1

0.872

CCNB1IP1

0.777

DERL1

0.738

RNF139

0.721

SSR3

0.699

SSR2

0.670

HSP90B1

0.614

SF3A3

0.600

PPP6R3

0.592

DEFB119

0.538

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCNB1IP1	HM13	ENSFCAP00000032609	ENSFCAP00000013601	Cyclin B1 interacting protein 1.	Histocompatibility minor 13.	0.777
CCNB1IP1	SF3A3	ENSFCAP00000032609	ENSFCAP00000057597	Cyclin B1 interacting protein 1.	Splicing factor 3a subunit 3.	0.757
DEFB119	HM13	ENSFCAP00000029822	ENSFCAP00000013601	Defensin beta 119.	Histocompatibility minor 13.	0.538
DERL1	HM13	ENSFCAP00000023495	ENSFCAP00000013601	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Histocompatibility minor 13.	0.738
DERL1	HSP90B1	ENSFCAP00000023495	ENSFCAP00000058313	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Heat shock protein 90 beta family member 1.	0.527
DERL1	RNF139	ENSFCAP00000023495	ENSFCAP00000060082	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ring finger protein 139.	0.858
HM13	CCNB1IP1	ENSFCAP00000013601	ENSFCAP00000032609	Histocompatibility minor 13.	Cyclin B1 interacting protein 1.	0.777
HM13	DEFB119	ENSFCAP00000013601	ENSFCAP00000029822	Histocompatibility minor 13.	Defensin beta 119.	0.538
HM13	DERL1	ENSFCAP00000013601	ENSFCAP00000023495	Histocompatibility minor 13.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.738
HM13	HMOX1	ENSFCAP00000013601	ENSFCAP00000062192	Histocompatibility minor 13.	Heme oxygenase 1.	0.872
HM13	HSP90B1	ENSFCAP00000013601	ENSFCAP00000058313	Histocompatibility minor 13.	Heat shock protein 90 beta family member 1.	0.614
HM13	PPP6R3	ENSFCAP00000013601	ENSFCAP00000022369	Histocompatibility minor 13.	Protein phosphatase 6 regulatory subunit 3.	0.592
HM13	RNF139	ENSFCAP00000013601	ENSFCAP00000060082	Histocompatibility minor 13.	Ring finger protein 139.	0.721
HM13	SF3A3	ENSFCAP00000013601	ENSFCAP00000057597	Histocompatibility minor 13.	Splicing factor 3a subunit 3.	0.600
HM13	SSR2	ENSFCAP00000013601	ENSFCAP00000046265	Histocompatibility minor 13.	Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.	0.670
HM13	SSR3	ENSFCAP00000013601	ENSFCAP00000020951	Histocompatibility minor 13.	Signal sequence receptor subunit 3.	0.699
HMOX1	HM13	ENSFCAP00000062192	ENSFCAP00000013601	Heme oxygenase 1.	Histocompatibility minor 13.	0.872
HSP90B1	DERL1	ENSFCAP00000058313	ENSFCAP00000023495	Heat shock protein 90 beta family member 1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.527
HSP90B1	HM13	ENSFCAP00000058313	ENSFCAP00000013601	Heat shock protein 90 beta family member 1.	Histocompatibility minor 13.	0.614
PPP6R3	HM13	ENSFCAP00000022369	ENSFCAP00000013601	Protein phosphatase 6 regulatory subunit 3.	Histocompatibility minor 13.	0.592