STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SQSTM1Sequestosome 1. (443 aa)    
Predicted Functional Partners:
NBR1
NBR1 autophagy cargo receptor.
    
 0.997
GABARAPL2
GABA type A receptor associated protein like 2.
   
 0.996
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.995
TBK1
TANK binding kinase 1.
    
 0.995
WDFY3
WD repeat and FYVE domain containing 3.
   
 0.988
CYLD
CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.
    
 0.980
ENSFCAP00000026617
Ubiquitin-like domain-containing protein.
   
 0.979
KEAP1
Kelch like ECH associated protein 1.
    
 0.975
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.974
MAP3K3
Uncharacterized protein.
    
 0.971
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.