STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRICKLE1Prickle planar cell polarity protein 1. (830 aa)    
Predicted Functional Partners:
DVL2
Dishevelled segment polarity protein 2.
    
 0.989
VANGL1
Vang-like protein.
    
 0.987
DVL1
Dishevelled segment polarity protein 1.
    
 0.983
DVL3
Dishevelled segment polarity protein 3.
    
 0.959
PRICKLE2
Prickle planar cell polarity protein 2.
    
 
0.906
PRICKLE4
Uncharacterized protein.
     
0.900
VANGL2
Vang-like protein.
    
 0.833
FZD3
Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.795
CELSR1
Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.
   
 0.741
SMURF2
E3 ubiquitin-protein ligase.
    
 0.739
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.