STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRPHPeripherin; Belongs to the intermediate filament family. (469 aa)    
Predicted Functional Partners:
NEFM
Neurofilament medium; Belongs to the intermediate filament family.
    
 
0.903
NEFL
Neurofilament light; Belongs to the intermediate filament family.
    
 
0.903
NEFH
Neurofilament heavy; Belongs to the intermediate filament family.
    
 
0.903
PARP8
Poly [ADP-ribose] polymerase.
      
 0.605
PDE6G
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G- protein-mediated phototransduction in vertebrate rods and cones (By similarity).
      
 0.590
PARP16
Poly [ADP-ribose] polymerase.
      
 0.539
PARP4
Poly [ADP-ribose] polymerase.
      
 0.532
TIPARP
TCDD inducible poly(ADP-ribose) polymerase.
      
 0.487
MAFF
MAF bZIP transcription factor F.
      
 0.455
PARP14
Poly [ADP-ribose] polymerase.
      
 0.447
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.