STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NXF1Nuclear RNA export factor 1. (618 aa)    
Predicted Functional Partners:
NXT1
Nuclear transport factor 2 like export factor 1.
    
 0.998
ALYREF
Aly/REF export factor.
    
 0.997
NXT2
Nuclear transport factor 2 like export factor 2.
    
 0.974
UPF3A
UPF3A regulator of nonsense mediated mRNA decay.
    
 0.962
THOC5
THO complex 5.
    
 0.961
UPF3B
UPF3B regulator of nonsense mediated mRNA decay.
    
 0.954
EIF4A3
Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.
   
 0.951
NUP98
Nucleoporin 98.
    
 0.854
TPR
Translocated promoter region, nuclear basket protein.
   
 0.851
ENSFCAP00000058905
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
   
 0.838
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.