Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LSSTerpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (733 aa)    
Predicted Functional Partners:
CYP51A1
Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 0.993
SQLE
Squalene epoxidase.
  
 
 0.989
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
 
 
 0.972
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
   
 
 0.965
SC5D
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 0.959
DHCR24
24-dehydrocholesterol reductase.
   
 
 0.958
NSDHL
NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.
 
 
 0.954
IDI1
Isopentenyl-diphosphate delta isomerase 1.
  
 
 0.917
DHCR7
7-dehydrocholesterol reductase.
   
  
 0.903
ERG28
Ergosterol biosynthesis 28 homolog.
    
 
 0.860
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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