node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGTR2 | EDN1 | ENSFCAP00000013050 | ENSFCAP00000013767 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | 0.927 |
AGTR2 | EDN2 | ENSFCAP00000013050 | ENSFCAP00000013015 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | Endothelin-2; Endothelins are endothelium-derived vasoconstrictor peptides. Belongs to the endothelin/sarafotoxin family. | 0.944 |
AGTR2 | EDN3 | ENSFCAP00000013050 | ENSFCAP00000057011 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | Uncharacterized protein. | 0.886 |
AGTR2 | EDNRA | ENSFCAP00000013050 | ENSFCAP00000040752 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. | 0.744 |
AGTR2 | EDNRB | ENSFCAP00000013050 | ENSFCAP00000043816 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. | 0.744 |
BDKRB2 | EDN1 | ENSFCAP00000031421 | ENSFCAP00000013767 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | 0.922 |
BDKRB2 | EDNRA | ENSFCAP00000031421 | ENSFCAP00000040752 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. | 0.905 |
BDKRB2 | EDNRB | ENSFCAP00000031421 | ENSFCAP00000043816 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. | 0.909 |
ECE1 | EDN1 | ENSFCAP00000013479 | ENSFCAP00000013767 | Endothelin converting enzyme 1. | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | 0.962 |
ECE1 | EDN2 | ENSFCAP00000013479 | ENSFCAP00000013015 | Endothelin converting enzyme 1. | Endothelin-2; Endothelins are endothelium-derived vasoconstrictor peptides. Belongs to the endothelin/sarafotoxin family. | 0.583 |
ECE1 | EDN3 | ENSFCAP00000013479 | ENSFCAP00000057011 | Endothelin converting enzyme 1. | Uncharacterized protein. | 0.705 |
ECE1 | EDNRA | ENSFCAP00000013479 | ENSFCAP00000040752 | Endothelin converting enzyme 1. | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. | 0.614 |
ECE1 | EDNRB | ENSFCAP00000013479 | ENSFCAP00000043816 | Endothelin converting enzyme 1. | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. | 0.658 |
ECE2 | EDN1 | ENSFCAP00000029603 | ENSFCAP00000013767 | Endothelin converting enzyme 2. | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | 0.898 |
ECE2 | EDN3 | ENSFCAP00000029603 | ENSFCAP00000057011 | Endothelin converting enzyme 2. | Uncharacterized protein. | 0.610 |
ECE2 | EDNRA | ENSFCAP00000029603 | ENSFCAP00000040752 | Endothelin converting enzyme 2. | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. | 0.438 |
ECE2 | EDNRB | ENSFCAP00000029603 | ENSFCAP00000043816 | Endothelin converting enzyme 2. | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. | 0.455 |
EDN1 | AGTR2 | ENSFCAP00000013767 | ENSFCAP00000013050 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | 0.927 |
EDN1 | BDKRB2 | ENSFCAP00000013767 | ENSFCAP00000031421 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. | 0.922 |
EDN1 | ECE1 | ENSFCAP00000013767 | ENSFCAP00000013479 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | Endothelin converting enzyme 1. | 0.962 |