Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF40Rho guanine nucleotide exchange factor 40. (1517 aa)    
Predicted Functional Partners:
OR7G2
Olfactory receptor.
     
 0.588
MRPS18B
Mitochondrial ribosomal protein S18B.
      
 0.580
LRRC45
Leucine rich repeat containing 45.
      
 0.580
L1TD1
LINE1 type transposase domain containing 1.
      
 0.580
KANSL1L
KAT8 regulatory NSL complex subunit 1 like.
      
 0.580
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1.
      
 0.579
PARP8
Poly [ADP-ribose] polymerase.
      
 0.579
RPTN
EF-hand domain-containing protein.
    
 
 0.579
MLF1
Myeloid leukemia factor 1.
      
 0.577
SALL4
Spalt like transcription factor 4.
      
 0.492
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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