Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCMBPMinichromosome maintenance complex binding protein. (642 aa)    
Predicted Functional Partners:
MCM5
Minichromosome maintenance complex component 5; Belongs to the MCM family.
   
 
 0.983
MCM3
DNA helicase; Belongs to the MCM family.
   
 
 0.981
MCM6
DNA helicase; Belongs to the MCM family.
   
 
 0.972
MCM2
DNA helicase; Belongs to the MCM family.
   
 
 0.959
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 
 0.925
ENSFCAP00000061455
Uncharacterized protein.
   
 
 0.925
MCM4
DNA helicase; Belongs to the MCM family.
   
 
 0.914
ENSFCAP00000061943
Uncharacterized protein.
   
 
 0.914
MCM9
Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family.
   
 
 0.896
PRIM2
DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.
   
  
 0.824
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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