STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGMS1Sphingomyelin synthase 1. (407 aa)    
Predicted Functional Partners:
SMPD1
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
     
 0.979
ASAH2
Neutral ceramidase.
 
   
 0.974
CERK
Ceramide kinase.
     
 0.973
CERS2
Ceramide synthase 2.
     
 0.973
UGCG
UDP-glucose ceramide glucosyltransferase.
     
 0.968
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.957
DEGS1
Delta 4-desaturase, sphingolipid 1.
   
 
 0.950
SMPD3
Sphingomyelin phosphodiesterase 3.
     
 0.950
ACER2
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
     
 0.948
CERS6
Ceramide synthase 6.
     
 0.948
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.