STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTSBCathepsin B; Belongs to the peptidase C1 family. (339 aa)    
Predicted Functional Partners:
CTSD
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
   
 0.966
NLRP3
NLR family pyrin domain containing 3.
    
 0.937
BCL2
BCL2 apoptosis regulator.
   
 
 0.937
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 
 0.914
BCL2L1
BCL2 like 1.
     
 0.907
LAMP1
Lysosomal associated membrane protein 1.
   
 
 0.898
LGMN
Legumain.
   
 
 0.814
TMPRSS2
Transmembrane serine protease 2; Belongs to the peptidase S1 family.
     
 0.758
CTSF
Cathepsin F; Belongs to the peptidase C1 family.
  
0.741
ANXA2
Annexin.
   
 0.716
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.