STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UPRTUracil phosphoribosyltransferase homolog. (306 aa)    
Predicted Functional Partners:
UCK2
Uridine-cytidine kinase; Belongs to the uridine kinase family.
 
 0.992
UCK1
PRK domain-containing protein.
 
 0.976
UCKL1
Uridine-cytidine kinase; Belongs to the uridine kinase family.
  
0.929
GDA
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
  
 
 0.871
AMDHD1
Amidohydrolase domain containing 1.
  
 
 0.870
SMUG1
Single-strand-selective monofunctional uracil-DNA glycosylase 1.
   
 0.839
ADAT2
Adenosine deaminase tRNA specific 2.
   
 0.839
PDCD11
Programmed cell death 11.
   
 
 0.830
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
    
 0.816
SHMT1
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
  
 0.801
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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