STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPINK5Serine peptidase inhibitor, Kazal type 5. (1061 aa)    
Predicted Functional Partners:
KLK5
Kallikrein related peptidase 5; Belongs to the peptidase S1 family.
   
 0.960
KLK6
Kallikrein related peptidase 6; Belongs to the peptidase S1 family.
   
 0.947
KLK14
Kallikrein related peptidase 14; Belongs to the peptidase S1 family.
   
 0.666
CDSN
Corneodesmosin.
      
 0.658
DSG1
Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
  
 0.626
ACTL9
Actin like 9; Belongs to the actin family.
      
 0.622
SPINK4
Serine peptidase inhibitor, Kazal type 4.
      
 0.619
KLK11
Kallikrein related peptidase 11; Belongs to the peptidase S1 family.
   
 0.612
KLK12
Kallikrein related peptidase 12; Belongs to the peptidase S1 family.
   
 0.583
KLK8
Kallikrein related peptidase 8; Belongs to the peptidase S1 family.
   
 0.583
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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