Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMC8Transmembrane channel-like protein. (723 aa)    
Predicted Functional Partners:
MYBPC1
Myosin binding protein C, slow type.
    
 0.727
KCNG4
Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family.
    
 
 0.715
SYNGR2
Synaptogyrin.
      
 0.685
HEPHL1
Hephaestin like 1; Belongs to the multicopper oxidase family.
    
 0.684
CKM
Creatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family.
      
 0.659
CKB
Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family.
      
 0.659
CKMT1A
Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family.
      
 0.659
CKMT2
Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family.
      
 0.651
IDUA
Iduronidase alpha-L-.
    
 0.625
CIB1
Calcium and integrin binding 1.
    
 0.615
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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