STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FGD3FYVE, RhoGEF and PH domain containing 3. (739 aa)    
Predicted Functional Partners:
CDC42-2
Uncharacterized protein.
   
 0.944
FGD1
FYVE, RhoGEF and PH domain containing 1.
  
  
0.906
GNG12
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
     
 0.904
GNG14
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
     
  0.900
NOC3L
Nucleolar complex protein 3 homolog.
      
 0.692
TCEA2
Transcription elongation factor A2.
      
 0.673
TLCD3B
TLC domain ceramide synthase 3B.
      
 0.645
GIGYF1
GRB10 interacting GYF protein 1.
      
 0.629
EPB41L4A
Erythrocyte membrane protein band 4.1 like 4A.
      
 0.625
CORO1A
Coronin; Belongs to the WD repeat coronin family.
   
  
 0.566
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (18%) [HD]