STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF6Interferon regulatory factor 6. (480 aa)    
Predicted Functional Partners:
RIPK4
Receptor interacting serine/threonine kinase 4.
   
 0.682
GRHL3
Grainyhead like transcription factor 3.
   
 
 0.654
SASH1
SAM and SH3 domain containing 1.
  
 
 
 0.589
ADM
Adrenomedullin.
      
 0.568
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
 0.555
ARHGAP29
Rho GTPase activating protein 29.
   
  
 0.500
ESRP2
Epithelial splicing regulatory protein 2.
   
  
 0.491
VAX1
Ventral anterior homeobox 1.
   
 
 0.469
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.469
OVOL1
Ovo like transcriptional repressor 1.
   
  
 0.465
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (28%) [HD]