Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PARPBPPARP1 binding protein. (607 aa)    
Predicted Functional Partners:
CKAP2L
Cytoskeleton associated protein 2 like.
   
  0.741
DHX16
DEAH-box helicase 16.
   
 0.737
NSRP1
Nuclear speckle splicing regulatory protein 1.
   
 0.720
HMMR
Hyaluronan mediated motility receptor.
   
 
 0.710
PPIL1
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
 0.709
GPKOW
G-patch domain and KOW motifs.
   
 0.706
CENPE
Centromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.694
PMCH
Pro-melanin concentrating hormone.
   
  
 0.687
PPWD1
Peptidylprolyl isomerase domain and WD repeat containing 1.
   
 0.681
CWC22
CWC22 spliceosome associated protein homolog.
   
 0.665
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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