STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP11Matrix metallopeptidase 11. (488 aa)    
Predicted Functional Partners:
PCSK4
Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family.
    
 0.799
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
    
 0.799
SPP1
Secreted phosphoprotein 1.
     
 0.707
FBLN1
Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
   
 0.633
TIMP1
TIMP metallopeptidase inhibitor 1.
   
 0.631
TIMP2
TIMP metallopeptidase inhibitor 2.
   
 0.616
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.598
MMP7
Matrilysin; Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase; Belongs to the peptidase M10A family.
  
  
0.594
MMP20
Matrix metallopeptidase 20.
  
0.515
MGP
Matrix Gla protein; Associates with the organic matrix of bone and cartilage.
      
 0.501
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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