Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PACSIN1Protein kinase C and casein kinase substrate in neurons 1. (444 aa)    
Predicted Functional Partners:
PACSIN3
Protein kinase C and casein kinase substrate in neurons 3.
    
  0.983
PACSIN2
Protein kinase C and casein kinase substrate in neurons 2.
    
  0.952
COBLL1
Cordon-bleu WH2 repeat protein like 1.
    
 
 0.935
HTT
Huntingtin.
    
 0.848
RAI14
Retinoic acid induced 14.
   
 
 0.828
WASL
WASP like actin nucleation promoting factor.
    
 
 0.738
AMPH
Amphiphysin.
   
  
 0.664
DNM2
Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
    
 
 0.650
DNM1
Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
    
 
 0.650
ARHGAP17
Rho GTPase activating protein 17.
   
 
 0.648
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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