STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EML4EMAP like 4. (1006 aa)    
Predicted Functional Partners:
ALK
Tyrosine-protein kinase receptor.
   
 0.985
KRAS
Uncharacterized protein.
    
 0.962
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.943
HRAS
HRas proto-oncogene, GTPase.
    
 0.922
NRAS
NRAS proto-oncogene, GTPase.
    
 0.922
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
     
 0.917
JAK2
Tyrosine-protein kinase.
   
 0.916
PLCG1
Phosphoinositide phospholipase C.
     
 0.916
JAK3
Tyrosine-protein kinase.
   
 0.910
JAK1
Tyrosine-protein kinase.
   
 0.907
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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