STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCAPSREBF chaperone. (1278 aa)    
Predicted Functional Partners:
SREBF2
Sterol regulatory element binding transcription factor 2.
   
 0.967
SREBF1
Sterol regulatory element binding transcription factor 1.
   
 0.963
INSIG1
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.
   
 0.857
INSIG2
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.
   
 0.857
NPC2
NPC intracellular cholesterol transporter 2.
   
 0.830
MYCN
MYCN proto-oncogene, bHLH transcription factor.
   
 0.726
MBTPS1
Membrane bound transcription factor peptidase, site 1.
   
 
 0.674
FASN
Fatty acid synthase.
   
  
 0.530
CB1H4orf33
Chromosome B1 C4orf33 homolog.
      
 0.515
PAQR3
Progestin and adipoQ receptor family member 3.
   
  
 0.481
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.