Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TFAP2BTranscription factor AP-2 beta. (476 aa)    
Predicted Functional Partners:
TFAP2A
Transcription factor AP-2 alpha.
   
 0.944
TFAP2D
Transcription factor AP-2 delta.
   
 0.794
LYPLAL1
Lysophospholipase like 1.
      
 0.710
TFAP2C
Transcription factor AP-2 gamma.
   
 0.698
KCTD15
Potassium channel tetramerization domain containing 15.
   
 0.643
KCTD1
Potassium channel tetramerization domain containing 1.
   
 0.643
ZNF597
Zinc finger protein 597.
    
 0.621
ZNF432
Zinc finger protein 432.
    
 0.621
RBAK
RB associated KRAB zinc finger.
    
 0.621
ZNF287
Uncharacterized protein.
    
 0.620
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (10%) [HD]