Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DENND3DENN domain containing 3. (1272 aa)    
Predicted Functional Partners:
RAB12
RAB12, member RAS oncogene family.
    
 0.875
ULK1
Unc-51 like autophagy activating kinase 1.
    
 0.842
DENND5A
DENN domain containing 5A.
    
 
 0.751
DENND5B
DENN domain containing 5B.
    
 
 0.736
RAB43
RAB43, member RAS oncogene family.
     
 0.708
TSKU
Tsukushi, small leucine rich proteoglycan.
    
 
 0.703
ISY1
Uncharacterized protein.
      
 0.702
ZSCAN2
Zinc finger and SCAN domain containing 2.
      
 0.702
ULK2
Unc-51 like autophagy activating kinase 2.
    
 0.669
RAB28
RAB28, member RAS oncogene family.
    
 0.646
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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