PAX3 protein (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PAX3

Paired box 3. (484 aa)

Predicted Functional Partners:

NCOA1

0.936

PAX7

0.913

SOX10

0.887

MYF5

0.861

MYOG

0.815

MYOD1

0.753

TIMM22

0.751

ZIC1

0.667

TIMM10

0.662

EDNRB

0.660

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDNRB	PAX3	ENSFCAP00000043816	ENSFCAP00000015658	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.	Paired box 3.	0.660
EDNRB	SOX10	ENSFCAP00000043816	ENSFCAP00000002581	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.	SRY-box transcription factor 10.	0.716
MYF5	MYOD1	ENSFCAP00000013924	ENSFCAP00000004602	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.411
MYF5	MYOG	ENSFCAP00000013924	ENSFCAP00000029126	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenin.	0.686
MYF5	PAX3	ENSFCAP00000013924	ENSFCAP00000015658	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Paired box 3.	0.861
MYF5	PAX7	ENSFCAP00000013924	ENSFCAP00000049078	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Paired box 7.	0.900
MYOD1	MYF5	ENSFCAP00000004602	ENSFCAP00000013924	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.411
MYOD1	MYOG	ENSFCAP00000004602	ENSFCAP00000029126	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenin.	0.740
MYOD1	PAX3	ENSFCAP00000004602	ENSFCAP00000015658	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Paired box 3.	0.753
MYOD1	PAX7	ENSFCAP00000004602	ENSFCAP00000049078	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Paired box 7.	0.820
MYOG	MYF5	ENSFCAP00000029126	ENSFCAP00000013924	Myogenin.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.686
MYOG	MYOD1	ENSFCAP00000029126	ENSFCAP00000004602	Myogenin.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.740
MYOG	PAX3	ENSFCAP00000029126	ENSFCAP00000015658	Myogenin.	Paired box 3.	0.815
MYOG	PAX7	ENSFCAP00000029126	ENSFCAP00000049078	Myogenin.	Paired box 7.	0.899
NCOA1	PAX3	ENSFCAP00000042028	ENSFCAP00000015658	Nuclear receptor coactivator.	Paired box 3.	0.936
NCOA1	PAX7	ENSFCAP00000042028	ENSFCAP00000049078	Nuclear receptor coactivator.	Paired box 7.	0.615
PAX3	EDNRB	ENSFCAP00000015658	ENSFCAP00000043816	Paired box 3.	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.	0.660
PAX3	MYF5	ENSFCAP00000015658	ENSFCAP00000013924	Paired box 3.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.861
PAX3	MYOD1	ENSFCAP00000015658	ENSFCAP00000004602	Paired box 3.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.753
PAX3	MYOG	ENSFCAP00000015658	ENSFCAP00000029126	Paired box 3.	Myogenin.	0.815