STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARL16ADP ribosylation factor like GTPase 16. (112 aa)    
Predicted Functional Partners:
USP21
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
 
 0.924
RNF125
Ring finger protein 125.
    
 
 0.784
IRF2BPL
Interferon regulatory factor 2 binding protein like.
    
 
 0.734
ARL13A
ADP ribosylation factor like GTPase 13A.
      
 0.732
CYLD
CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.
    
 
 0.632
ARL9
ADP ribosylation factor like GTPase 9; Belongs to the small GTPase superfamily. Arf family.
    
 0.551
TRIM65
Tripartite motif containing 65.
   
 0.550
ARL5B
ADP ribosylation factor like GTPase 5B; Belongs to the small GTPase superfamily. Arf family.
    
 0.522
PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
    
   0.505
ACTR10
Actin related protein 10; Belongs to the actin family.
    
 0.496
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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