STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LEMD3LEM domain containing 3. (915 aa)    
Predicted Functional Partners:
SMAD1
Mothers against decapentaplegic homolog.
   
 
 0.861
CDC5L
Cell division cycle 5 like.
   
 
 0.829
WIF1
WNT inhibitory factor 1.
      
 0.778
EMILIN2
Elastin microfibril interfacer 2.
      
 0.763
BANF1
Barrier to autointegration factor 1.
   
 0.753
SMAD3
Mothers against decapentaplegic homolog.
   
 
 0.748
SMAD2
Mothers against decapentaplegic homolog.
   
 
 0.748
ADAMTSL3
ADAMTS like 3.
      
 0.746
EMD
Emerin.
     
 0.739
MSRB3
Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.
 
    
 0.739
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.