STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIPA1Signal-induced proliferation-associated 1. (1047 aa)    
Predicted Functional Partners:
RAP1A
RAP1A, member of RAS oncogene family.
    
 0.943
RAP1B
RAP1B, member of RAS oncogene family.
    
 0.943
AFDN
Afadin, adherens junction formation factor.
    
 0.923
DPF2
Double PHD fingers 2.
      
 0.704
MAP3K11
Mitogen-activated protein kinase kinase kinase.
   
 
 0.674
EPS8L1
EPS8 like 1.
      
 0.622
RAPGEF4
Rap guanine nucleotide exchange factor 4.
   
 0.596
ELL3
Elongation factor for RNA polymerase II 3.
      
 0.592
ADCY4
Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
  
 0.579
RASGRP3
RAS guanyl releasing protein 3.
     
 0.552
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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