STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDHAF4Succinate dehydrogenase complex assembly factor 4. (107 aa)    
Predicted Functional Partners:
SDHAF3
Succinate dehydrogenase complex assembly factor 3.
   
 
 0.767
ENSFCAP00000056878
Uncharacterized protein.
   
 
 0.767
COA4
Cytochrome c oxidase assembly factor 4 homolog.
      
 0.758
SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
   
 
 0.734
LYRM7
LYR motif containing 7; Belongs to the complex I LYR family.
      
 0.681
SDHAF1
Succinate dehydrogenase complex assembly factor 1; Belongs to the complex I LYR family.
      
 0.643
NDUFAF2
NADH:ubiquinone oxidoreductase complex assembly factor 2.
      
 0.554
COX19
Cytochrome c oxidase assembly factor COX19.
   
  
 0.548
SDHAF2
Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.
      
 0.547
NDUFAF1
NADH:ubiquinone oxidoreductase complex assembly factor 1.
      
 0.543
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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