STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KDF1Keratinocyte differentiation factor 1. (397 aa)    
Predicted Functional Partners:
RIF1
Replication timing regulatory factor 1.
    
 
 0.605
RIPK4
Receptor interacting serine/threonine kinase 4.
   
 
 0.604
RAB25
RAB25, member RAS oncogene family.
   
  
 0.586
C1orf210
Chromosome 1 open reading frame 210.
   
  
 0.545
AP1M2
AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
   
  
 0.542
FOXP1
Forkhead box P1.
      
 0.523
ELMO3
Engulfment and cell motility 3.
   
  
 0.475
ARHGEF16
Rho guanine nucleotide exchange factor 16.
   
  
 0.465
PRSS35
Serine protease 35.
      
 0.455
DHRS13
Dehydrogenase/reductase 13.
      
 0.455
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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