STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K11Mitogen-activated protein kinase kinase kinase. (865 aa)    
Predicted Functional Partners:
CDC42-2
Uncharacterized protein.
   
 0.960
MAP2K7
Mitogen-activated protein kinase kinase 7.
   
0.945
MAPK8IP1
Mitogen-activated protein kinase 8 interacting protein 1.
    
 0.940
MAPK8IP2
Mitogen-activated protein kinase 8 interacting protein 2.
    
 0.934
MAPK8IP3
Mitogen-activated protein kinase 8 interacting protein 3.
   
 0.927
MAP4K1
Mitogen-activated protein kinase kinase kinase kinase 1; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
   
0.916
LTBP3
Latent transforming growth factor beta binding protein 3.
 
  
 0.839
FAM89B
Family with sequence similarity 89 member B.
   
 
 0.833
RNASEH2C
Ribonuclease H2 subunit C.
    
 0.752
DPF2
Double PHD fingers 2.
      
 0.718
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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