M3WZY2_FELCA protein (Felis catus) - STRING interaction network

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Score

M3WZY2_FELCA

DUF1968 domain-containing protein. (220 aa)

Predicted Functional Partners:

LOC101081297

0.926

ENSFCAP00000059917

0.852

B2M

0.835

RPA2

0.835

ITK

0.798

CD3E

0.786

ENSFCAP00000041968

0.763

CD2

0.717

FGB

0.705

ENSFCAP00000059218

0.682

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B2M	CD3E	ENSFCAP00000011347	ENSFCAP00000059396	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	0.615
B2M	LOC101081297	ENSFCAP00000011347	ENSFCAP00000030752	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Ig-like domain-containing protein; Belongs to the MHC class I family.	0.905
B2M	M3WZY2_FELCA	ENSFCAP00000011347	ENSFCAP00000019923	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	DUF1968 domain-containing protein.	0.835
CD2	CD3E	ENSFCAP00000060337	ENSFCAP00000059396	CD2 molecule.	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	0.927
CD2	ENSFCAP00000059917	ENSFCAP00000060337	ENSFCAP00000059917	CD2 molecule.	IGv domain-containing protein.	0.457
CD2	ITK	ENSFCAP00000060337	ENSFCAP00000009237	CD2 molecule.	Tyrosine-protein kinase.	0.776
CD2	M3WZY2_FELCA	ENSFCAP00000060337	ENSFCAP00000019923	CD2 molecule.	DUF1968 domain-containing protein.	0.717
CD3E	B2M	ENSFCAP00000059396	ENSFCAP00000011347	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	0.615
CD3E	CD2	ENSFCAP00000059396	ENSFCAP00000060337	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	CD2 molecule.	0.927
CD3E	ENSFCAP00000059917	ENSFCAP00000059396	ENSFCAP00000059917	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	IGv domain-containing protein.	0.727
CD3E	ITK	ENSFCAP00000059396	ENSFCAP00000009237	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	Tyrosine-protein kinase.	0.924
CD3E	M3WZY2_FELCA	ENSFCAP00000059396	ENSFCAP00000019923	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	DUF1968 domain-containing protein.	0.786
CD3E	RPA2	ENSFCAP00000059396	ENSFCAP00000030959	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	Replication protein A2.	0.615
ENSFCAP00000041968	ENSFCAP00000059218	ENSFCAP00000041968	ENSFCAP00000059218	Ig-like domain-containing protein.	IG domain-containing protein.	0.547
ENSFCAP00000041968	ENSFCAP00000059917	ENSFCAP00000041968	ENSFCAP00000059917	Ig-like domain-containing protein.	IGv domain-containing protein.	0.705
ENSFCAP00000041968	M3WZY2_FELCA	ENSFCAP00000041968	ENSFCAP00000019923	Ig-like domain-containing protein.	DUF1968 domain-containing protein.	0.763
ENSFCAP00000059218	ENSFCAP00000041968	ENSFCAP00000059218	ENSFCAP00000041968	IG domain-containing protein.	Ig-like domain-containing protein.	0.547
ENSFCAP00000059218	ENSFCAP00000059917	ENSFCAP00000059218	ENSFCAP00000059917	IG domain-containing protein.	IGv domain-containing protein.	0.724
ENSFCAP00000059218	M3WZY2_FELCA	ENSFCAP00000059218	ENSFCAP00000019923	IG domain-containing protein.	DUF1968 domain-containing protein.	0.682
ENSFCAP00000059917	CD2	ENSFCAP00000059917	ENSFCAP00000060337	IGv domain-containing protein.	CD2 molecule.	0.457