STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARAFA-Raf proto-oncogene, serine/threonine kinase. (659 aa)    
Predicted Functional Partners:
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
  
 
0.991
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.
   
 0.986
KRAS
Uncharacterized protein.
   
 0.979
YWHAZ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.
   
 0.977
MAP2K1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
0.977
NRAS
NRAS proto-oncogene, GTPase.
   
 0.975
RAP1A
RAP1A, member of RAS oncogene family.
   
 0.973
RAP1B
RAP1B, member of RAS oncogene family.
   
 0.973
MAP2K2
Protein kinase domain-containing protein.
   
0.972
HRAS
HRas proto-oncogene, GTPase.
   
 0.966
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.