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TYR protein (Felis catus) - STRING interaction network
"TYR" - Tyrosinase in Felis catus
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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TYRTyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4- dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6- dihydroxyindole) to indole-5,6 quinone; Belongs to the tyrosinase family (530 aa)    
Predicted Functional Partners:
PMEL
Premelanosome protein (663 aa)
     
   
  0.948
TH
Tyrosine hydroxylase (525 aa)
     
 
  0.947
MITF
Microphthalmia-associated transcription factor (487 aa)
     
 
  0.935
DDC
Dopa decarboxylase (aromatic L-amino acid decarboxylase) (480 aa)
         
  0.925
OCA2
Uncharacterized protein; Oculocutaneous albinism II (539 aa)
     
   
  0.905
GOT1
Aspartate aminotransferase; Glutamic-oxaloacetic transaminase 1, soluble (405 aa)
     
 
  0.905
GOT2
Aspartate aminotransferase; Glutamic-oxaloacetic transaminase 2, mitochondrial (430 aa)
     
 
  0.904
TPO
Thyroid peroxidase (946 aa)
     
 
  0.903
TAT
Tyrosine aminotransferase (458 aa)
     
 
  0.902
ENSFCAG00000023472
Amine oxidase (526 aa)
         
    0.900
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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