STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCDH17Protocadherin 17. (1196 aa)    
Predicted Functional Partners:
GFRA2
GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.
      
 0.605
GFRA3
GDNF family receptor alpha 3.
      
 0.602
MAP3K7CL
MAP3K7 C-terminal like.
    
 0.546
TMCC3
Transmembrane and coiled-coil domain family 3.
      
 0.538
INSYN2A
Inhibitory synaptic factor 2A.
     
 0.533
RIPK4
Receptor interacting serine/threonine kinase 4.
    
 0.520
CYFIP2
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
    
 0.486
TSPAN15
Tetraspanin.
     
 0.480
SAMD5
Sterile alpha motif domain containing 5.
   
  
 0.478
MALRD1
MAM and LDL receptor class A domain containing 1.
    
 0.476
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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