Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (200 aa)    
Predicted Functional Partners:
CYTH2
Uncharacterized protein.
    
 0.913
GBF1
Golgi brefeldin A resistant guanine nucleotide exchange factor 1.
    
 0.890
CYTH4
Cytohesin 4.
    
 0.863
NCKAP1L
NCK associated protein 1 like.
   
 0.799
WASF3
WASP family member 3.
    
 0.791
ARF6
Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.
   
  0.785
ABI1
Abl interactor 1.
    
 0.784
LOC101089059
Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.
     
  0.772
COPB1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 0.771
ARFGAP2
ADP ribosylation factor GTPase activating protein 2.
   
 0.736
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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