STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLF1SMC5-SMC6 complex localization factor 1. (1059 aa)    
Predicted Functional Partners:
CDC45
Cell division cycle 45.
   
 
 0.974
WRN
WRN RecQ like helicase.
   
 0.969
BARD1
BRCA1 associated RING domain 1.
   
0.966
PSMD12
Proteasome 26S subunit, non-ATPase 12.
    
 0.966
ATR
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
    
 0.944
RAD18
RAD18 E3 ubiquitin protein ligase.
    
 
 0.925
MCM5
Minichromosome maintenance complex component 5; Belongs to the MCM family.
   
 
 0.923
RHNO1
RAD9-HUS1-RAD1 interacting nuclear orphan 1.
    
 0.908
TP53BP1
Tumor protein p53 binding protein 1.
    
 0.902
RAD9B
RAD9 checkpoint clamp component B.
    
 0.900
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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